
简 历
I. 个人信息
赵鹏,博士,讲师,2019年毕业于北京化工大学,后继续博士后工作,2021年入职永利集团,生物工程系。
II. 研究方向
细胞培养与代谢工程、天然产物生物合成、高值化学品的微生物转化.
III. 科研项目
1. 基于浓度响应型适配体开关的 CRISPRi/a 平台调控天然产物 石杉碱甲生物合成. 北京市自然科学基金(5232005).
2. 利用 CRISPRa/i 和产物浓度响应型适配体开关调控长途径天然产物戊二酸的合成. 北京市教育委员会科技计划一般项目(KM202310020012).
3. 石杉碱甲生物合成中环闭合模块关键酶挖掘. 永利官网青年教师科研创新能力提升计划 (QJKC2022021).
IV. 代表论文
1. Zhao P, Li Q Y, Tian P F, Tan T W. Switching metabolic flux by engineering tryptophan operon-assisted CRISPR interference system in Klebsiella pneumoniae. Metabolic Engineering, 2021, 65: 30-41.
2. Zhao P, Ren M R, Ge X Z, Tian P F, Tan T W. Development of orthogonal T7 expression system in Klebsiella pneumoniae. Biotechnology and Bioengineering, 2020, 117: 2446-2459.
3. Zhao P, Ma C L, Xu L D, Tian P F. Exploiting tandem repetitive promoters for high-level production of 3-hydroxypropionic acid. Applied Microbiology and Biotechnology, 2019, 103(10): 4017-4031.
4. Zhao P, Wang W J, Tian P F. Development of cyclic AMP receptor protein-based artificial transcription factor for intensifying gene expression. Applied Microbiology and Biotechnology, 2018, 102(4): 1673-1685.
5. Zhao P, Tian P F. Biosynthesis pathways and strategies for improving 3hydroxypropionic acid production in bacteria. World Journal of Microbiology and Biotechnology, 2021, 37: 117.
V. 联系方式
邮政地址: 北京市昌平区回龙观镇北农路7号,永利集团,邮政编码102206.
电子邮箱:zpyugioh@163.com
Curriculum Vitae
VI.
Personal information
Peng Zhao, Ph.D, Lecturer, Department of Bioengineering, College of Bioscience and Resources Environment, Beijing University of Agriculture.
Dr. Zhao graduated from Beijing University of Chemical Technology in 2019 and continued the postdoctoral work, and then joined Beijing University of Agriculture in 2021.
VII. Research interests
The research interests include cell culture and metabolic engineering, biosynthesis of natural products, and microbial transformation of high-value chemicals.
VIII. Research Projects
4. The CRISPRi/a platform based on a concentration-responsive aptamer switch regulates the biosynthesis of the natural product huperzine A. Beijing Natural Science Foundation project (5232005).
5. Regulation the biosysthesis of long-pathway natural product glutaric acid by CRISPRa/i and product concentration-responsive aptamer riboswitch. Beijing Municipal Education Commission scientific research plan general project (KM202310020012).
6. Extraction of key enzymes in huperzine A biosynthetic ring closure module. Scientific research innovation ability enhancement program of Beijing University of Agriculture (QJKC2022021).
IX. Representative works
1. Zhao P, Li Q Y, Tian P F, Tan T W. Switching metabolic flux by engineering tryptophan operon-assisted CRISPR interference system in Klebsiella pneumoniae. Metabolic Engineering, 2021, 65: 30-41.
2. Zhao P, Ren M R, Ge X Z, Tian P F, Tan T W. Development of orthogonal T7 expression system in Klebsiella pneumoniae. Biotechnology and Bioengineering, 2020, 117: 2446-2459.
3. Zhao P, Ma C L, Xu L D, Tian P F. Exploiting tandem repetitive promoters for high-level production of 3-hydroxypropionic acid. Applied Microbiology and Biotechnology, 2019, 103(10): 4017-4031.
4. Zhao P, Wang W J, Tian P F. Development of cyclic AMP receptor protein-based artificial transcription factor for intensifying gene expression. Applied Microbiology and Biotechnology, 2018, 102(4): 1673-1685.
5. Zhao P, Tian P F. Biosynthesis pathways and strategies for improving 3hydroxypropionic acid production in bacteria. World Journal of Microbiology and Biotechnology, 2021, 37: 117.
X. Contact information
Postal address: College of Bioscience and Resources Environment, Beijing University of Agriculture, No. 7, Beinong Road, Huilongguan, Changping, Beijing, 102206
E-mail: zpyugioh@163.com